86 Must Read House, M.D. Facts For Hugh Laurie Fans

House, M.D is a highly acclaimed medical drama that aired from 2004 to 2012 with Hugh Laurie in the lead role. The show revolves around the brilliant yet unconventional diagnostician Dr. Gregory House and is set in the fictional Princeton-Plainsboro Teaching Hospital. House follows the medical team as they tackle complex and mysterious cases that have stumped other doctors.

Dr. Gregory House is a brilliant but misanthropic physician known for his razor-sharp wit, cynicism, and unorthodox approach to medicine. He often clashes with his colleagues and challenges established medical practices. Despite his abrasive personality, House possesses an unparalleled ability to solve medical mysteries, earning him a reputation as a diagnostic genius.

The ensemble cast features a diverse group of doctors who work alongside House. Dr. Lisa Cuddy, portrayed by Lisa Edelstein, serves as the hospital's Dean of Medicine and frequently clashes with House over his unorthodox methods. Robert Sean Leonard plays Dr. James Wilson, House's best friend and oncologist, who provides a moral counterbalance to House's unconventional behaviour.

The team of young doctors includes Dr. Eric Foreman (Omar Epps), a former juvenile delinquent turned neurologist; Dr. Allison Cameron (Jennifer Morrison), a compassionate and empathetic immunologist; and Dr. Robert Chase (Jesse Spencer), an ambitious yet morally ambiguous intensivist.

The show's success can be attributed to its intelligent writing, which combines medical jargon, moral dilemmas, and moments of dark humour. House tackles thought-provoking themes such as the limits of medical ethics, the complexities of human nature, and the pursuit of truth in the face of adversity.

“Anytime you try to summarise a show in one word, you sound like an ass. It's about truth.” - David Shore

Our House, M.D facts include the many references between House and Sherlock Holmes, why Kal Penn’s character left suddenly and what American Idol has to do with its success.

1. House Creator David Shore Also Developed The Good Doctor

The concept for the series was developed by Paul Attanasio, with David Shore serving as the creator and primarily responsible for the iconic titular character.

The executive producers of House included David Shore, Paul Attanasio, Katie Jacobs (Attanasio's business partner), and film director Bryan Singer. David Shore is also known for his shows Battle Creek and The Good Doctor.

2. House Has Been Ranked Continuously Among The Top 10 US TV Shows

House consistently ranked among the top 10 series in the United States from its second to fourth seasons. It was also widely distributed and watched in 66 countries, earning the title of the most-watched television program worldwide in 2008. 

On February 8, 2012, Fox announced that the ongoing eighth season would be the final one. The series finale aired on May 21, 2012, following an hour-long retrospective episode.

3. House Is Inspired By A New York Times Column

In 2004, David Shore, Paul Attanasio, and Katie Jacobs pitched an untitled series to Fox, envisioning a medical detective show in the style of CSI. They wanted to create a hospital-based whodunit where doctors would investigate symptoms and their underlying causes. 

The inspiration for this medical procedural drama came from the column "Diagnosis" in The New York Times Magazine, written by physician Lisa Sanders, who worked at Yale–New Haven Hospital. The fictional Princeton–Plainsboro Teaching Hospital (PPTH) in the series is modelled after this teaching institution.

4. The Network Didn’t Want “Doctors In White Coats Roaming The Hallways”

Despite Fox's interest in a medical show, network president Gail Berman made it clear when discussing House that she didn't want to see doctors in white coats roaming the hallways.

5. House Was Originally Named “Chasing Zebras, Circling the Drain”

The show initially had the working title Chasing Zebras, Circling the Drain, with "zebra" representing an unusual diagnosis and "circling the drain" referring to terminal cases.

The original concept centred around a team of doctors working together to diagnose mysterious illnesses. However, David Shore realised that the show needed a captivating central character who could delve into patients' personal lives, uncover their secrets, and accurately diagnose their ailments. This shift led to a more character-driven focus, and the character's name, House, became the show's title.

6. David Shore Wanted House To Mock Patients Before Leaving The Room

The pilot episode, directed by Bryan Singer, was titled "Everybody Lies," reflecting the show's premise that people often hide the truth. Berton Roueché, a writer known for his features on peculiar medical cases, served as an inspiration for early episode storylines. Shore's own experience as a patient at a teaching hospital played a role in shaping the title character. He wanted to explore a character who would mock patients before leaving the room, based on his fear of being ridiculed by doctors after his own clueless moments.

7. House Was Originally In A Wheelchair

Originally, the idea was for House to use a wheelchair, but Fox rejected it. Instead, the network requested a reimagination of the character, ultimately leading to House having a leg injury from a misdiagnosis. This physical condition requires him to use a cane and causes chronic pain, leading to his reliance on narcotic pain medication.

By incorporating these elements and developing the characters further, House emerged as a unique and compelling medical drama with a focus on the complex and flawed central character.

8. There Are Many Sherlock Holmes References In House

Throughout the series House, references to the fictional detective Sherlock Holmes can be found. David Shore, a fan of Sherlock Holmes, admired the character's indifference toward his clients, which influenced House's demeanour. 

The similarities between House and Holmes are evident in their reliance on deductive reasoning, psychology, and their reluctance to take on uninteresting cases. Both characters are musicians and have a taste for drugs, with House dependent on Vicodin and Holmes using cocaine recreationally. 

House's relationship with Dr. James Wilson mirrors the dynamic between Holmes and Dr. John Watson - their names are even similar. In fact, House's diagnostic team embodies the Watson role in the series. 

Even House's name and address, 221B Baker Street, pay homage to Holmes!

“It's not a show about addiction, but you can't throw something like this into the mix and not expect it to be noticed and commented on. There have been references to the amount of his consumption increasing over time.” - David Shore on House's Vicodin addiction

9. House References Specific Sherlock Holmes Stories

House also features specific episode references to Sherlock Holmes stories. 

• The pilot episode's patient is named Rebecca Adler, a nod to Irene Adler from Holmes' "A Scandal in Bohemia." 

• In the season two finale, House is shot by a character credited as "Moriarty," Holmes's arch-nemesis. 

• In "It's a Wonderful Lie" (season four), House receives a second-edition Conan Doyle book as a Christmas gift. 

• In "The Itch" (season five), House's keys and Vicodin rest atop a copy of Conan Doyle's The Memoirs of Sherlock Holmes. 

• In "Joy to the World" (season five), House uses a book by Joseph Bell, the inspiration for Holmes, to deceive his team. 

• Another episode features a patient who wrote a detective book series with an ambiguous ending reminiscent of "The Final Problem." 

• The series finale also pays homage to Holmes' apparent death in Conan Doyle's intended conclusion, "The Final Problem."

10. Hugh Laurie Directed A Season 6 Episode

Over the course of the first six seasons, more than two dozen writers contributed to the series, with the most prolific being Kaplow, Blake, Shore, Friend, Lerner, Moran, and Egan. The directors with the most episodes were Deran Sarafian and Greg Yaitanes. Hugh Laurie himself directed an episode in season six.

11. House Had Several Medical Advisors Including Columnist Lisa Sanders

Elan Soltes held the position of visual effects supervisor since the show's inception. Lisa Sanders, an assistant clinical professor of medicine at the Yale School of Medicine and author of the "Diagnosis" column that inspired House, served as a technical advisor. The series had three different doctors who reviewed the medical aspects of the show. Bobbin Bergstrom, a registered nurse, was the on-set medical adviser.

12. Producers Thought Hugh Laurie Was American After His Audition

Initially, the producers of House were seeking a quintessentially American actor for the role of House. Bryan Singer, in particular, was adamant about hiring an American actor. However, during the casting session, Hugh Laurie, an English actor, sent in an audition tape from Namibia, where he was filming another project. He filmed the audition in a hotel bathroom, the only place with sufficient light, and apologised for its appearance. 

Despite Singer comparing the tape to a "bin Laden video," Laurie's performance impressed him. Singer was unaware that Laurie was English due to his convincing American accent, which Laurie attributed to watching a lot of TV and movies during his youth. 

13. Patrick Dempsey Auditioned For The Role Of House

Other actors like Denis Leary, David Cross, Rob Morrow, and Patrick Dempsey were considered for the part, Laurie ultimately won over the producers and was cast as House.

14. Hugh Laurie Initially Thought He Was Cast In A Supporting Role

Laurie initially thought the central character of the show was Dr. James Wilson, assuming House was a supporting role until he received the full script of the pilot episode. 

15. Hugh Laurie Felt Bad Playing A Fictionalised Version Of His Father

Being the son of a medical doctor himself, Hugh Laurie felt guilty about being paid to portray a fictional version of his father.

16. Hugh Laurie Was One Of The Highest Paid Actors On Network Television

Hugh Laurie’s salary increased significantly over the course of the series, reaching around $400,000 per episode by the fifth season and $700,000 per episode for the final season, making him one of the highest-paid actors on network television.

17. Bryan Singer Is Responsible For Casting Wilson And Cuddy

Robert Sean Leonard, a long-time friend of Bryan Singer, auditioned for the role of Dr. Wilson. Lisa Edelstein, known for her role on The West Wing, received a copy of the pilot script from Singer and was attracted to the quality of the writing and her character's dynamic dialogue with House, leading to her casting as Dr. Lisa Cuddy.

18. Patrick Dempsey Also Auditioned For The Role Of Chase

Australian actor Jesse Spencer initially believed the show would be similar to General Hospital but changed his mind after reading the scripts. He convinced the producers to make his character, Dr. Robert Chase, Australian. 

Patrick Dempsey also auditioned for the role of Chase but went on to gain fame as Dr. Derek Shepherd on Grey's Anatomy. 

19. Eric Foreman Was Also A Character In That ‘70s Show

Omar Epps, inspired by his previous role on ER, played Dr. Eric Foreman, despite the similarity in names to the character Eric Forman from That '70s Show, which aired concurrently on Fox. 

20. Jennifer Morrison Thought Her Audition Was A Disaster

Jennifer Morrison thought her audition for Dr. Allison Cameron was a disaster, but Bryan Singer had already wanted to cast her based on her previous performances.

21. Crew Were Kept In The Dark About The New Regular Cast Members

At the end of the third season, House dismisses Chase, while Foreman and Cameron resign. House then assembles a new diagnostic team, ultimately hiring three new regular cast members: Lawrence Kutner (Kal Penn), Chris Taub (Peter Jacobson), and Remy "Thirteen" Hadley (Olivia Wilde). 

The producers originally planned to add two new full-time actors, with Foreman returning to bring the team back up to three members. However, they decided to expand the team with three new regulars instead. The selection process for the new team was kept secret from the cast and producers until the final moments of each episode. 

Amber "Cutthroat Bitch" Volakis (Anne Dudek), who was initially rejected by House, later appeared as a recurring character in subsequent seasons.

22. Edelstein, Epps and Sean Were Asked To Reduce Their Salaries

Following the seventh season, the contracts of Lisa Edelstein, Omar Epps, and Robert Sean Leonard expired. As a cost-cutting measure, the actors were asked to accept reduced salaries. Epps and Leonard reached agreements with the producers, but Edelstein did not, leading to her departure from the show before its eighth season.

23. House Is Well Known For Its “Walk and Talk” Style

House frequently utilises the "walk and talk" filming technique, which has been popularised by shows like St. Elsewhere, ER, Sports Night, and The West Wing. 

This technique involves tracking shots that capture characters walking and talking as they move between locations. Executive producer Katie Jacobs explained that the show often employs this technique to create a sense of urgency and intensity in scenes. She also highlighted the visual impact of Hugh Laurie's height (6'2"), which makes the walk-and-talk scenes stand out. 

24. Critics Praised House’s “Inside The Human Body” Effects

The New Yorker's Nancy Franklin praised the show's special effects, likening the visuals of patients' innards to the popping of bubble wrap. Critics noted the intricate camera work that takes viewers inside the body, using miniature effects and motion control photography instead of relying heavily on computer-generated imagery. The sets are often filled with unscripted props, allowing Laurie to improvise and reveal more about his character and the story.

25. The Pilot Episode Was Filmed In Vancouver

While the House pilot episode was filmed in Vancouver, subsequent episodes were primarily shot on the Fox lot in Century City, Los Angeles. Bryan Singer, the director of the pilot, chose a hospital near his hometown in West Windsor, New Jersey, as the fictional setting for the show. 

26. Princeton University Provides The Aerial Shots For Princeton-Plainsboro

Princeton University's Frist Campus Center provides the aerial views of Princeton-Plainsboro Teaching Hospital seen in the series. 

Some scenes were filmed at the University of Southern California for the season three episode "Half-Wit," which featured guest stars Dave Matthews and Kurtwood Smith. Additionally, for House's sixth season, the abandoned Greystone Park Psychiatric Hospital in Parsippany-Troy Hills, New Jersey, was used as the fictional Mayfield Psychiatric Hospital.

27. House Started With A Short Opening Title Sequence

The opening sequence of the show begins with an MRI image of a head, prominently featuring the boxed "H" logo, symbolising a hospital. This image is then overlaid with a shot of Dr. House's face from the pilot episode, while the full title of the show appears across his face. House's image gradually fades, and the show's title is underlined with the addition of the "M.D." designation, completing the show's logo. This was the extent of the title sequence in the pilot episode.

In subsequent episodes, a longer title sequence was introduced, featuring the names of the six main cast members and creator David Shore. Hugh Laurie's name appears first, followed by the other cast members' names listed in alphabetical order (Edelstein, Epps, Leonard, Morrison, and Spencer), and finally, David Shore's name.

28. The House Title Sequence Was Nominated For An Emmy Award

According to Katie Jacobs, one of the House producers, most of the background images in the title sequence do not hold specific meaning. However, the final image, which shows the text "created by David Shore" superimposed on a human neck, symbolises Shore as "the brain of the show." This title sequence was nominated for a Primetime Emmy Award for Outstanding Main Title Design in 2005.

29. The House Theme Song Is Teardrop By Massive Attack

The opening theme of the show, as heard in the United States, features instrumental segments of the song "Teardrop" by Massive Attack. This choice was partly influenced by the distinct tempo of the song, which mimics the sound of a human heartbeat. 

During the season-four finale, an acoustic version of "Teardrop" performed by José González, with guitar and vocals, is played as background music.

30. House Was A Hit With Film And TV Critics

House was well-received upon its debut, with critics considering it a standout amidst Fox's reality show-dominated schedule at the time. TV Guide's Matt Roush described the show as an "uncommon cure for the common medical drama," while David Bianculli of the New York Daily News applauded the high calibre of acting and script. 

The character of Gregory House received widespread critical acclaim. Tom Shales of The Washington Post hailed him as “the most electrifying new main character to grace television in years”, while Rob Owen of the Pittsburgh Post-Gazette found him “fascinatingly unsympathetic”. 

31. House Has Been Compared To Hawkeye And Poirot

House has been compared to fictional detectives such as Nero Wolfe, Hercule Poirot, and Adrian Monk, as well as to Perry Cox, the cantankerous doctor from the TV show Scrubs. 

In fact, a book-length study of the series identified a strong connection between House and another iconic TV doctor, Hawkeye Pierce from MAS*H. 

32. The Writers Guild Of America West Rate House Highly

In a survey conducted by the Writers Guild of America West members in 2013, House was ranked as the 74th best-written television series.

33. House’s Success In Ratings May Be Helped By American Idol

During its first season, House ranked twenty-fourth among all TV series and was the ninth-most popular primetime show among women. With the support of the highly popular American Idol as its lead-in, the following three seasons of House consistently secured spots in the top ten across all viewership. The show reached its peak Nielsen ratings during its third season, attracting an average of 19.4 million viewers per episode. The unexpectedly large audience response surprised the production team, according to Jacobs. 

In the fifth season, the viewership averaged 12.0 million per episode, placing the show in nineteenth place overall but still making it Fox's most popular program after American Idol.

34. Frozen Is The Most Watched House Episode With 29 Million Viewers

The most-watched episode of House is the season four episode "Frozen," which aired after Super Bowl XLII and garnered slightly over 29 million viewers. This episode ranked third for the week, matching the ratings of American Idol and only falling behind the Super Bowl itself and the post-game show. 

35. Hugh Laurie Was Consistently Nominated For Emmy Awards

Hugh Laurie was consistently nominated for an Emmy Award for Outstanding Lead Actor in a Drama Series in multiple years, including 2005, 2007, 2008, 2009, 2010, and 2011. The Emmy board also recognized House with nominations for Outstanding Drama Series in 2006, 2007, 2008, and 2009, although the show did not win the award.

In 2005, David Shore won a writing Emmy for the season one episode "Three Stories," and he also received the Humanitas Prize in 2006. Director Greg Yaitanes earned a Primetime Emmy Award for Outstanding Directing for a Drama Series in 2008 for his work on the two-part finale of season four, titled "House's Head."

36. House Received Six Golden Globes Nominations

House received six Golden Globe Award nominations and won twice. Hugh Laurie was nominated six times for the Golden Globe Award for Best Actor - Television Series Drama, winning in 2006 and 2007. In 2008, the series received its first nomination for the Golden Globe Award for Best Television Series - Drama, but it did not win in the category the following year.

37. House Is One Of “The Most Distinctive New Doctor Dramas In A Decade”

The show was honoured with a Peabody Award in 2005, recognized for its unorthodox lead character and cases that were likened to those of a medical Sherlock Holmes, making House one of the most distinctive new doctor dramas in a decade. The American Film Institute (AFI) also included House in its 2005 list of 10 Television Programs of the Year.

38. House’s Accolades Do Not Stop There…

In 2011, House received four People's Choice Awards, including Favorite TV Drama, and Favorite Dramatic Actor and Actress for Hugh Laurie and Lisa Edelstein. Laurie also won the Screen Actors Guild's award for Outstanding Performance by a Male Actor in a Drama Series in 2007 and 2009. Writer Lawrence Kaplow earned a Writers Guild of America Award in 2006 for the season two episode "Autopsy." Additionally, the show received a Creative Arts Emmy Award for prosthetic makeup in 2007.

39. Hugh Laurie Was Voted As TV’s Sexiest Man

Hugh Laurie was recognised as "TV's Sexiest Man" by TV Guide in 2005, and in a separate poll in 2008, Gregory House was voted the second-sexiest television doctor ever, second only to ER's Doug Ross portrayed by George Clooney.

40. House Was The Most Watched TV Show In The World

In 2008, House achieved global distribution in a total of 66 countries. It captivated an audience of over 81.8 million viewers worldwide, making it the most-watched television show across the globe. It significantly surpassed the viewership of other leading TV dramas of the previous two years, namely CSI and CSI: Miami. The following year, House ranked second globally, following CSI.

In the United Kingdom, the first four seasons of House were broadcast on Five, while Sky1 acquired first-run rights starting from season five. 

41. House Was Available For Online Download On iTunes

Viewers had the opportunity to access episodes of House online for download. Platforms such as Amazon Video on Demand, iTunes Store, and the Zune Marketplace offered episodes from all eight seasons. 

However, in 2007, a dispute between NBCUniversal and Apple Inc. briefly resulted in the fourth season being temporarily unavailable on iTunes. The conflict arose from NBCUniversal's desire to increase the per-episode price to $4.99. Fortunately, in September 2008, it was reported that the issue between Apple and NBC had been resolved. 

Some episodes were also available for streaming on Fox's official House webpage, and the entire series was previously available on Netflix until April 2017.

42. There Were Limited House TShirts Available For Charity

Starting from April 23, 2007, a limited-time charity auction featured T-shirts bearing the iconic phrase "Everybody Lies," which were available for purchase on Housecharitytees.com. Another set of shirts with the phrase "Normal's Overrated" was also sold, with all proceeds going to the National Alliance on Mental Illness (NAMI). The cast and crew of House actively participated in fundraising events for NAMI and appeared in advertisements for the organisation published in Seventeen and Rolling Stone. 

These collective efforts raised substantial funds, amounting to hundreds of thousands of dollars, for the charity. The goal of their association with NAMI was to reduce the stigma surrounding mental illness.

43. There Is A House Soundtrack Album

On September 18, 2007, Nettwerk released the House M.D. Original Television Soundtrack album. This compilation included full-length versions of songs featured in House, as well as previously unreleased tracks specially recorded for the series. It provided fans with a comprehensive collection of the show's memorable music. 

44. There Is A House Mobile Game

In 2008, the Spanish game company Exelweiss developed a mobile phone game based on House, which was released in both Spanish and English versions.

45. There Is Also A House Video Game

In June 2009, Legacy Interactive announced a licensing agreement with Universal Pictures Digital Platforms Group (UPDPG) to create a video game inspired by the series.

In this game, players assumed the roles of House's diagnostic team and tackled five unusual medical cases. As part of the gameplay, there was a minigame where players guided a giant sandwich through a maze resembling a restaurant placemat, while avoiding hungry physicians on its way to Dr. House's office. The initial release of the game received a negative review from The A.V. Club, earning an F rating. However, Legacy Interactive worked on updating the game, and by August 2010, improvements were made to enhance the player's experience.

46. Chase Actually Provides More Accurate Diagnoses Than Anyone

While some characters occasionally suggest that Dr. Robert Chase (played by Jesse Spencer) lacks intelligence, he actually provides more accurate diagnoses than any other supporting character throughout the series.

Dr. Robert Chase specialises in intensive care as an intensivist, a specialty that is relatively new and uncommon in the United States but well-established in Australia, his home country.

47. The Name House Could Be Linked To A Real Medical Term

In emergency room settings, when doctors admit patients with a documented history of drug use or addiction, the abbreviation "H.O.USE" (History of Use) is often used in their patient charts.

48. Gregory House Is A Polyglot

Dr. House is a polyglot, proficient in multiple languages including English, Spanish, Portuguese, Russian, French, Hindi (to some extent), and Mandarin.

49. Hugh Laurie Is The “Most Watched Leading Man On Television”

Hugh Laurie holds the world record for being the "most watched leading man on television" due to his portrayal of Gregory House.

50. The Daily Express Claimed Hugh Laurie Suffered From Pain After The Role

In September 2009, the British tabloid The Daily Express reported that Hugh Laurie began experiencing physical injuries as a result of years of walking with his character's distinctive limp.

51. There Is An Orson Welles Connection

One of the movie posters displayed in Dr. James Wilson's office, portrayed by Robert Sean Leonard, features Orson Welles' Touch of Evil (1958). In the film, Orson Welles portrays a detective with a leg impairment who solves crimes purely based on his intuition. This may have served as an influence for the development of Dr. Gregory House's character, played by Hugh Laurie.

In Dr. James Wilson's office, there are also posters from the movies Ordinary People (1980) directed by Robert Redford and Vertigo (1958) directed by Alfred Hitchcock.

52. Isn’t It Always Lupus?

As Lupus became a frequently suggested but misleading diagnosis throughout House, M.D., it eventually became a running joke on the show.

Another recurring pattern in the series is for House and his team to propose a diagnosis for a patient that turns out to be the correct diagnosis from the previous episode.

53. James Spencer’s Family Are In The Medical Profession

Jesse Spencer, who portrays Dr. Robert Chase, is one of the few members in his family who is not in the medical profession. His father is a radiologist, and his older brothers are oculoplastic surgeons and orthopaedic surgeons. Additionally, his younger sister works as an anaesthetist.

54. Fox Insisted House Have An Adversary

At the beginning of the first season, FOX insisted that House should have an adversary or someone who challenges his behaviour. Although creator David Shore initially had reservations about the idea, he introduced the character of Edward Vogler, portrayed by Chi McBride, stating that he would only appear in five episodes before leaving the show.

55. House And Hugh Laurie Inspired Lin-Manuel Miranda’s Hamilton

According to Lin-Manuel Miranda's book "Hamilton: The Revolution," the inspiration for the "Hamilton" song "You'll Be Back" came from his friendship with Hugh Laurie, which developed during Miranda's time as an actor on "House." Miranda mentioned that while having a drink with Hugh Laurie, he expressed his desire to write a breakup letter from King George to the colonies. Laurie immediately responded by wagging his finger and saying, "Aww, you'll be back." Miranda found it amusing and stored the idea for later use.

56. What Are The Diagnostic Team’s Specialties?

Although the Diagnostic Medicine team deals with a wide range of diseases, Dr. Gregory House and his colleagues hold titles in various subspecialties. Dr. Eric Foreman is a neurologist, Dr. Allison Cameron specialises in immunology and allergy, Dr. Robert Chase is an intensivist, Dr. Chris Taub is a plastic surgeon, Dr. Lawrence Kutner focused on sports medicine, and Dr. Remy "Thirteen" Hadley is an internist. 

Dr. House himself is double-certified in infectious disease and nephrology, as mentioned in season one, episode three, "Occam's Razor."

57. Hugh Laurie Joked House Could Have Dated Cameron, Cuddy and Wilson

During Hugh Laurie's appearance on Inside the Actors Studio, a student in the audience asked about Dr. House's potential romantic involvement with Dr. Allison Cameron, Dr. Lisa Cuddy, or Dr. James Wilson. Laurie responded by stating that if the show ran for a long enough duration, he believed House would be involved with all of them, though the order in which it unfolded was not his decision. 

He expressed that any of those relationships were plausible, acknowledging that two people can always find comfort or attraction. However, he jokingly mentioned that Robert Sean Leonard, who portrays Dr. Wilson, might have something to say about it.

58. The House Tagline Was Removed Due To Terrorism

The tagline "Humanity Is Overrated" was used in Finland. However, in November 2007, the phrase was used by a terrorist at a school shooting in the country. In response to the tragic event, the producers removed the phrase from the show's website.

59. Did You Notice the Dead Poets Society Quip?

In one scene, House comments, "Haven't you ever seen Dead Poets Society?" This references Robert Sean Leonard's role as Neil Perry in the film Dead Poets Society (1989).

60. Hugh Laurie Is The Only Cast Member In All 178 Episodes

Hugh Laurie, portraying Dr. Gregory House, is the only actor to appear in all 178 episodes of the series.

61. Foreman Never Repeats The Same Outfit

Dr. Eric Foreman, played by Omar Epps, never repeats the same outfit throughout the series.

62. Why Does House Have A Photo Of Stephen Colbert On His Desk?

After receiving an honorary doctorate in fine arts, Stephen Colbert, a television satirist, displayed pictures of famous television doctors who inspired him on the mantle-piece of his show's set. One of these pictures features Hugh Laurie as Dr. Gregory House. 

In response, the creators of House placed a picture of Colbert on Gregory House's desk in the show's fifth season, which can be seen occasionally. This playful interaction occurred because Laurie's show won an Emmy over Colbert's, and Laurie also received an OBE (Officer of the Most Excellent Order of the British Empire), which Colbert couldn't receive since he isn't British. As a result, Colbert added House to his enemies list.

63. Bryan Singer’s Production Company Is Named After A Line In Jaws

The production company credit at the end of the show for Bad Hat Harry Productions, owned by executive producer Bryan Singer, is a reference to the movie Jaws. The line "That's some bad hat, Harry" is spoken in the film.

64. Scrubs’ Dr. Kelso Also Says “Everybody Lies”

Dr. Gregory House's famous line, "Everybody lies," was used by another doctor in a medical sitcom called Scrubs about a year and a half before the pilot episode of House. Dr. Bob Kelso, portrayed by Ken Jenkins, says "Everybody lies, Dr. Turk" in season two, episode twelve, "My New Old Friend," after Dr. Chris Turk, played by Donald Faison, fails to prevent an elderly lady from driving home despite her claiming to be fine.

65. Does House Use His Cane On The Wrong Side?

The conventional way to use a cane is to hold it on the opposite side of the injured leg. However, Dr. House, true to his contrarian nature, insists on keeping his cane on the same side as his injured leg.

66. There Is A Connection With House And The O.C.

Dr. House frequently mentions watching The O.C. in the series. Interestingly, Olivia Wilde, who joined the cast as a regular in Season 4, also had a recurring role in Season 2 of The O.C.

67. Kyle MacLachlan Auditioned For Gregory House

Kyle MacLachlan auditioned for the role of Dr. House but described it as one of the worst auditions of his life.

68. Sándor Szakácsi Passed Away Before Dubbing All His House Episodes

Sándor Szakácsi, the Hungarian voice actor for Dr. House, passed away in March 2007. He had completed the dubbing for only eleven episodes of the second season. As a tribute to him, the television channel decided to use his unfinished work. Therefore, in the first half of Season 2, Episode 12, "Distractions," viewers could still hear Sándor's voice before János Kulka took over the role. The change occurred during a commercial break in the middle of a scene.

69. James Wilson Went TO McGill University in Montreal

In a promotional picture for the fourth season, Dr. James Wilson is seen wearing a McGill University sweater, implying that he received his undergraduate degree from McGill University in Montreal, Québec. It is also mentioned that he obtained a degree from Columbia University's "School of Oncology."

70. There Was Nearly A Lucas Douglas Spin Off

The character Lucas Douglas was created with the intention of establishing a spin-off series starring Michael Weston, but the producers ultimately decided against pursuing the spin-off.

71. House’s Apartment Is Also Amber And Wilson’s Apartment

House's apartment set doubles as Amber's apartment and Wilson's early apartment. Although the set is redressed for different characters, the layout remains the same, allowing for cost-saving in production.

72. Many Of The Cast Are Left Handed

Three out of the six original cast members are left-handed: Lisa Edelstein (Dr. Lisa Cuddy), Omar Epps (Dr. Eric Foreman), and Robert Sean Leonard (Dr. James Wilson).

73. Hugh Laurie Is A Talented Blues Musician

Dr. House is portrayed as a lover of jazz, piano playing, and electric guitars. In real life, Hugh Laurie is a talented blues musician who plays multiple instruments.

74. What Is House’s Motorcycle?

The motorcycle owned by Dr. House is a 2005 Honda CBR1000RR Repsol Replica.

75. Lisa Edelstein And Peter Jacobson Have Previously Worked Together

Lisa Edelstein (Dr. Lisa Cuddy) and Peter Jacobson (Dr. Chris Taub) appeared together in the film As Good as It Gets (1997), where they portrayed a couple insulted by Jack Nicholson's character, Melvin Udall, for sitting at his table in the restaurant.

76. A Lumbar Puncture Is Performed In Nearly Every Episode

The team in the series performs a "LP" or Lumbar Puncture in nearly every episode.

77. Omar Epps Appeared In More Episodes Of ER

"House" was Omar Epps's second-longest-running medical drama. His first medical drama was a stint as Dr. Dennis Gant in Season 3 of ER (1994).

78. Why Is Hadley Called “Thirteen”?

In Season 4, Dr. Remy Hadley, nicknamed "Thirteen" by House, earns her nickname during the early episodes. House interviews thirty potential candidates for his new team and assigns them numbers. Dr. Hadley ends up with the number "Thirteen," which is considered unlucky by many. Despite this, she becomes a part of the team, and the nickname sticks.

79. There Is A Psych Connection

Several actors and actresses from "House" also made appearances on "Psych" (2006). 

• Anne Dudek played Lucinda in the pilot episode of "Psych" and later portrayed Dr. Amber Volakis on "House" during Season 4 and part of Season 5.

• Jimmi Simpson appeared as Mary in Season 3, Episode 16 of "Psych" titled "An Evening with Mr. Yang" and later played Daniel Bresson in Season 5, Episode 15 of "House" titled "Unfaithful." 

• Michael Weston portrayed Adam Hornstock in Season 1, Episode 12 of "Psych" titled "Cloudy with a Chance of Murder" and also played Lucas Douglas on "House" during part of Season 5. 

• Frank Whaley appeared as Robert in Season 1, Episode 7 of "Psych" titled "Who Ya Gonna Call?" and later portrayed Mr. X in Season 4, Episode 5 of "House" titled "Mirror Mirror." 

• Kurtwood Smith played Brett Connors in Season 1, Episode 10 of "Psych" titled "Forget Me Not" and also appeared as Dr. Obyedkov in Season 3, Episode 15 of "House" titled "Half-Wit." 

• Scott Michael Campbell portrayed Wes Hildenbach in Season 1, Episode 6 of "Psych" titled "9 Lives" and later played Joe Luria on "House" in Season 2, Episodes 20 and 21 titled "Euphoria: Part 1" and "Euphoria: Part 2." 

• Mackenzie Astin appeared as Jason Cunningham in Season 3, Episode 15 of "Psych" titled "Tuesday the 17th" and also portrayed Alan Alston in Season 2, Episode 17 of "House" titled "All In." 

• Franka Potente played Nadia in Season 5, Episode 9 of "Psych" titled "One, Maybe Two, Ways Out" and later portrayed Lydia in "House" in Season 6, Episodes 1 and 2 titled "Broken, Part 1" and "Broken, Part 2."

80. Meat Loaf Makes A Cameo Appearance

Meat Loaf, the actor and musician, made a cameo appearance on House in 2009. Later in the season, a character named Dr. Paulson was introduced in Season 5, Episode 20 titled "Simple Explanation," possibly as a nod to Meat Loaf's character named Robert Paulson in the film Fight Club (1999).

81. Dr Allison Cameron Was Let Go To Show Integrity

Dr. Allison Cameron's departure from "House" was mainly because series creator David Shore wanted to depict that not every character around Dr. Gregory House would end up being "corrupt." Shore acknowledged that it was difficult to let go of Jennifer Morrison, but he believed that the story's integrity was more important.

82. David Shore Wanted Cuddy To Have A More Fitting Exit

Lisa Edelstein departed from the show after filming the season seven finale. According to series creator David Shore, if Edelstein had informed them earlier that she wouldn't be returning, he would have written the season finale differently and given the character a more fitting exit.

83. Jesse Spencer And Jennifer Morrison Got Engaged On House

Jesse Spencer and Jennifer Morrison got engaged in December 2006, coinciding with the filming of the initial episodes where their characters, Dr. Robert Chase and Dr. Allison Cameron, began a romantic relationship.

84. Hugh Laurie And House Have The Same Birthday

In the season two finale, "No Reason," when Dr. House was shot and hospitalised, his hospital wristband displays his date of birth as June 11, 1959, which interestingly aligns with Hugh Laurie's actual birth date.

85. House Keeps Wearing Kutner’s Secret Santa Watch

Throughout the series, House continues to wear the watch given to him by Kutner as a Secret Santa gift, symbolising a small reminder of House's humanity until the show's final episode.

86. Kal Penn Left To Work With President Barack Obama

In April 2009, Kal Penn revealed in an interview with Entertainment Weekly Magazine that his character was killed off on the show because he had requested to leave in order to work for the administration of President Barack Obama as the Associate Director in the White House Office of Public Liaison.

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